Siglec-1/CD169 Protein 5197-SL-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemSiglec-1/CD169 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number5197-SL-050
FormatLyophilized from a 0.2 µm filtered solution in PBS
Quantity50 ug
NCBI Full Gene Namesialic acid binding Ig like lectin 1
NCBI Gene AliasesCD169, SIGLEC-1, SN
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human Siglec-1 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Molecular WeightObserved: 175 kDa-190 kDa, reducing conditions
Theoretical: 173.9 kDa
Purity>80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecule NameSiglec-1/CD169
SpeciesHuman

Available conjugates: Unconjugated

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

(1) Selective tumor antigen vaccine delivery to human CD169⁺ antigen-presenting cells using ganglioside-liposomesProceedings of the National Academy of Sciences of the United States of AmericaNovember 3, 2020Affandi AJ, Grabowska J, Olesek K, Lopez Venegas M, Barbaria A, Rodríguez E, Mulder PPG, Pijffers HJ, Ambrosini M, Kalay H, et al.

(2) Anti-Siglec-1 antibodies block Ebola viral uptake and decrease cytoplasmic viral entryNature microbiologySeptember 1, 2019Perez-Zsolt D, Erkizia I, Pino M, García-Gallo M, Martin MT, Benet S, Chojnacki J, Fernández-Figueras MT, Guerrero D, Urrea V, et al.

(3) Membrane-wrapped nanoparticles probe divergent roles of GM3 and phosphatidylserine in lipid-mediated viral entry pathwaysProceedings of the National Academy of Sciences of the United States of AmericaSeptember 25, 2018Xu F, Bandara A, Akiyama H, Eshaghi B, Stelter D, Keyes T, Straub JE, Gummuluru S, Reinhard BM.

(4) The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosusArthritis research & therapyJuly 27, 2018Oliveira JJ, Karrar S, Rainbow DB, Pinder CL, Clarke P, Rubio García A, Al-Assar O, Burling K, Morris S, Stratton R, et al.

(5) An innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptidesJournal for immunotherapy of cancerApril 17, 2018Eggink LL, Roby KF, Cote R, Kenneth Hoober J.

(6) Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1eLifeSeptember 3, 2014Chen GY, Brown NK, Wu W, Khedri Z, Yu H, Chen X, van de Vlekkert D, D'Azzo A, Zheng P, Liu Y.

(8) Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acidsPloS oneJanuary 1, 2011Zou Z, Chastain A, Moir S, Ford J, Trandem K, Martinelli E, Cicala C, Crocker P, Arthos J, Sun PD.

Siglec-1/CD169 Protein from R&D Systems, a Bio-Techne Brand